Title : Role of the dopaminergic nigrostriatal pathway in methamphetamine-induced depression of the neostriatal serotonergic system.

Pub. Date : 1987 Mar 17

PMID : 2884120






2 Functional Relationships(s)
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1 The prevention of the decrease in neostriatal tryptophan hydroxylase (TPH) activity with a single dose of methamphetamine (MA) was attempted by lesioning the nigrostriatal dopaminergic projections with bilateral nigral injections of 6-hydroxydopamine (6-OHDA). Methamphetamine tryptophan hydroxylase 1 Rattus norvegicus
2 The prevention of the decrease in neostriatal tryptophan hydroxylase (TPH) activity with a single dose of methamphetamine (MA) was attempted by lesioning the nigrostriatal dopaminergic projections with bilateral nigral injections of 6-hydroxydopamine (6-OHDA). Methamphetamine tryptophan hydroxylase 1 Rattus norvegicus