Pub. Date : 2017 Sep 8
PMID : 28724635
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Heterodimers of the transcriptional factors NFATc3 and FosB mediate tissue factor expression for 15(S)-hydroxyeicosatetraenoic acid-induced monocyte trafficking. | Hydroxyeicosatetraenoic Acids | nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3 | Mus musculus |
| 2 | These observations indicate that 15(S)-HETE-induced monocyte/macrophage migration and trafficking require ROS-mediated CaMKIV activation leading to formation of NFATc3 and FosB heterodimer, which binds and activates the TF promoter. | Reactive Oxygen Species | nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3 | Mus musculus |