| Protein Name | nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 18021 |
| Gene Symbol | Nfatc3 |
| UniProt | Q3UZ64 (Q3UZ64_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
37
Total Number of Articles : 33 |
Description |
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3 |
| Gene Summary |
Enables DNA-binding transcription activator activity, RNA polymerase II-specific; chromatin binding activity; and transcription cis-regulatory region binding activity. Involved in T cell differentiation in thymus; positive regulation of artery morphogenesis; and positive regulation of biosynthetic process. Acts upstream of or within several processes, including calcineurin-NFAT signaling cascade; cardiac muscle hypertrophy in response to stress; and circulatory system development. Located in cytosol and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gland; and lung. Orthologous to human NFATC3 (nuclear factor of activated T cells 3). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |