PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28701304-2 2017 Extracellular accumulation of adenosine and subsequent activation of the ADORA2B receptor play important roles in regulating inflammation and fibrosis in IPF. Adenosine 30-39 adenosine A2b receptor Homo sapiens 73-80 28701304-3 2017 Additionally, alternatively activated macrophages (AAMs) expressing ADORA2B have been implicated in mediating adenosine"s effects in IPF. Adenosine 110-119 adenosine A2b receptor Homo sapiens 68-75 28701304-6 2017 We demonstrate that hypoxia-inducible factor 1-alpha (HIF1A) inhibition in late stages of bleomycin-induced injury attenuates pulmonary fibrosis in association, with reductions in ADORA2B expression in AAMs. Bleomycin 90-99 hypoxia inducible factor 1 subunit alpha Homo sapiens 20-52 28701304-6 2017 We demonstrate that hypoxia-inducible factor 1-alpha (HIF1A) inhibition in late stages of bleomycin-induced injury attenuates pulmonary fibrosis in association, with reductions in ADORA2B expression in AAMs. Bleomycin 90-99 hypoxia inducible factor 1 subunit alpha Homo sapiens 54-59