Pub. Date : 2017 Sep 1
PMID : 28687587
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Both pharmacological (1 microM AS1842856) and genetic (siRNA mediated) inhibition of FoxO1 decreased Pdk4/PDHK4 expression and subsequent PDH phosphorylation in H9c2 cardiac myocytes, whereas 10 microM dexamethasone-induced Pdk4/PDHK4 expression was abolished via pretreatment with 1 microM AS1842856. | 5-amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | forkhead box O1 | Mus musculus |
2 | Both pharmacological (1 microM AS1842856) and genetic (siRNA mediated) inhibition of FoxO1 decreased Pdk4/PDHK4 expression and subsequent PDH phosphorylation in H9c2 cardiac myocytes, whereas 10 microM dexamethasone-induced Pdk4/PDHK4 expression was abolished via pretreatment with 1 microM AS1842856. | 5-amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | forkhead box O1 | Mus musculus |