Protein Name forkhead box O1
Organism Mus musculus
Gene ID 56458
Gene Symbol

Foxo1

UniProt Q9R1E0 (FOXO1_MOUSE)
Relationships Total Number of functionally related compound(s) : 338
Total Number of Articles : 528
Description

forkhead box O1

Gene Summary

Enables several functions, including DNA binding activity; DNA-binding transcription factor activity, RNA polymerase II-specific; and promoter-specific chromatin binding activity. Involved in several processes, including cellular response to insulin stimulus; cellular response to nitric oxide; and negative regulation of fat cell differentiation. Acts upstream of or within several processes, including insulin receptor signaling pathway; neuronal stem cell population maintenance; and positive regulation of cellular biosynthetic process. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in alveolar rhabdomyosarcoma. Orthologous to human FOXO1 (forkhead box O1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • forkhead box protein O1
  • forkhead box O1a
  • forkhead box protein O1A
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Properties