Pub. Date : 2017 Apr 11
PMID : 28445987
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here, we identify and study the microRNAs that BRAFV600E regulates through the ERK pathway.By performing small RNA sequencing on A375 melanoma cells and a vemurafenib-resistant clone that was taken as negative control, we discover miR-204 and miR-211 as the miRNAs most induced by vemurafenib. | Vemurafenib | microRNA 211 | Homo sapiens |
| 2 | Here, we identify and study the microRNAs that BRAFV600E regulates through the ERK pathway.By performing small RNA sequencing on A375 melanoma cells and a vemurafenib-resistant clone that was taken as negative control, we discover miR-204 and miR-211 as the miRNAs most induced by vemurafenib. | Vemurafenib | microRNA 211 | Homo sapiens |
| 3 | In doing so, miR-211 serves as an effector of vemurafenib"s pro-pigmentation activity. | Vemurafenib | microRNA 211 | Homo sapiens |