Pub. Date : 2017 Jun
PMID : 28357609
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The Inhibitory Effect of C-phycocyanin Containing Protein Extract (C-PC Extract) on Human Matrix Metalloproteinases (MMP-2 and MMP-9) in Hepatocellular Cancer Cell Line (HepG2). | cytidylyl-(3'-5')-cytidine | matrix metallopeptidase 2 | Homo sapiens |
| 2 | The Inhibitory Effect of C-phycocyanin Containing Protein Extract (C-PC Extract) on Human Matrix Metalloproteinases (MMP-2 and MMP-9) in Hepatocellular Cancer Cell Line (HepG2). | cytidylyl-(3'-5')-cytidine | matrix metallopeptidase 9 | Homo sapiens |
| 3 | Herein, we have demonstrated that C-PC extract significantly reduced activity of MMP-2 by 55.13% and MMP-9 by 57.9% in HepG2 cells at 15 mug concentration. | cytidylyl-(3'-5')-cytidine | matrix metallopeptidase 2 | Homo sapiens |
| 4 | Herein, we have demonstrated that C-PC extract significantly reduced activity of MMP-2 by 55.13% and MMP-9 by 57.9% in HepG2 cells at 15 mug concentration. | cytidylyl-(3'-5')-cytidine | matrix metallopeptidase 9 | Homo sapiens |
| 5 | Together, these results indicate that C-PC, extract successfully inhibited MMP-2 and -9 at different levels of expression and TIMP-2 at a mRNA expression level; however, extract did not have any effect on MMP-1 expressed in MDA-MB231 and TIMP-1 expressed in HepG2 cells as well as the exact mechanism of inhibition of MMP-2, MMP-9 and TIMP-2 remained unclear. | cytidylyl-(3'-5')-cytidine | matrix metallopeptidase 2 | Homo sapiens |
| 6 | Together, these results indicate that C-PC, extract successfully inhibited MMP-2 and -9 at different levels of expression and TIMP-2 at a mRNA expression level; however, extract did not have any effect on MMP-1 expressed in MDA-MB231 and TIMP-1 expressed in HepG2 cells as well as the exact mechanism of inhibition of MMP-2, MMP-9 and TIMP-2 remained unclear. | cytidylyl-(3'-5')-cytidine | matrix metallopeptidase 2 | Homo sapiens |