Pub. Date : 2017
PMID : 28097065
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Upregulation of NOXA by 10-Hydroxycamptothecin plays a key role in inducing fibroblasts apoptosis and reducing epidural fibrosis. | 10-hydroxycamptothecin | phorbol-12-myristate-13-acetate-induced protein 1 | Rattus norvegicus |
| 2 | Our results showed that HCPT could induce apoptosis in fibroblasts and up-regulate the expression of NOXA. | 10-hydroxycamptothecin | phorbol-12-myristate-13-acetate-induced protein 1 | Rattus norvegicus |
| 3 | Also, immunohistochemical staining showed that the expression of NOXA increased as the concentrations of HCPT increased. | 10-hydroxycamptothecin | phorbol-12-myristate-13-acetate-induced protein 1 | Rattus norvegicus |
| 4 | Our findings are the first to demonstrate that upregulation of NOXA by HCPT plays a key role in inducing fibroblast apoptosis and in reducing epidural fibrosis. | 10-hydroxycamptothecin | phorbol-12-myristate-13-acetate-induced protein 1 | Rattus norvegicus |