Title : Synthesis and biological evaluation of hesperetin derivatives as agents inducing apoptosis.

Pub. Date : 2017 Jan 1

PMID : 27840137






3 Functional Relationships(s)
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1 Among the compounds, K-5b, hesperetin-7-butyrate, showed the half-maximal cell growth inhibitory concentration three times as low as that of hesperetin. hesperetin-7-butyrate keratin 78 Homo sapiens
2 Among the compounds, K-5b, hesperetin-7-butyrate, showed the half-maximal cell growth inhibitory concentration three times as low as that of hesperetin. hesperetin keratin 78 Homo sapiens
3 K-5b decreased the cell viability to a larger extent than hesperetin and triggered apoptosis more efficiently than hesperetin in an apoptosis detection assay using fluorescein isothiocyanate-labeled annexin V. Fluorescein-5-isothiocyanate keratin 78 Homo sapiens