Pub. Date : 2016 Nov 11
PMID : 27694439
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Mechanisms of Insertion of dCTP and dTTP Opposite the DNA Lesion O6-Methyl-2"-deoxyguanosine by Human DNA Polymerase eta. | O(6)-methyl-2'-deoxyguanosine | DNA polymerase eta | Homo sapiens |
| 2 | Comparison of the hpol eta active site configurations with either O6-MeG:dC or O6-MeG:dT bound compared with the corresponding situations in structures of complexes of Sulfolobus solfataricus Dpo4, a bypass pol that favors C relative to T by a factor of ~4, helps rationalize the more error-prone synthesis opposite the lesion by hpol eta. | O(6)-methyl-2'-deoxyguanosine | endothelin receptor type A | Homo sapiens |
| 3 | Comparison of the hpol eta active site configurations with either O6-MeG:dC or O6-MeG:dT bound compared with the corresponding situations in structures of complexes of Sulfolobus solfataricus Dpo4, a bypass pol that favors C relative to T by a factor of ~4, helps rationalize the more error-prone synthesis opposite the lesion by hpol eta. | O(6)-methyl-2'-deoxyguanosine | endothelin receptor type A | Homo sapiens |