Protein Name | endothelin receptor type A |
---|---|
Organism | Homo sapiens |
Gene ID | 1909 |
Gene Symbol | EDNRA |
UniProt | P25101 (EDNRA_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
1710
Total Number of Articles : 1749 |
Description |
endothelin receptor type A |
Gene Summary |
This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] |
synonyms |
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Properties | |