Title : β-asarone increases MEF2D and TH levels and reduces α-synuclein level in 6-OHDA-induced rats via regulating the HSP70/MAPK/MEF2D/Beclin-1 pathway: Chaperone-mediated autophagy activation, macroautophagy inhibition and HSP70 up-expression.

Pub. Date : 2016 Oct 15

PMID : 27444243






1 Functional Relationships(s)
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1 Our results also showed thatbeta-asarone treatment reduced protein and mRNA levels of alpha-syn, Beclin-1 and LC3B, but increased HSP70, TH, MEF2D, HSC70, LAMP-2A and p62 levels compared to the 6-OHDA model group. thatbeta-asarone KH RNA binding domain containing, signal transduction associated 1 Rattus norvegicus