PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27444243-0 2016 beta-asarone increases MEF2D and TH levels and reduces alpha-synuclein level in 6-OHDA-induced rats via regulating the HSP70/MAPK/MEF2D/Beclin-1 pathway: Chaperone-mediated autophagy activation, macroautophagy inhibition and HSP70 up-expression. asarone 0-12 myocyte enhancer factor 2D Rattus norvegicus 23-28 27444243-0 2016 beta-asarone increases MEF2D and TH levels and reduces alpha-synuclein level in 6-OHDA-induced rats via regulating the HSP70/MAPK/MEF2D/Beclin-1 pathway: Chaperone-mediated autophagy activation, macroautophagy inhibition and HSP70 up-expression. asarone 0-12 tyrosine hydroxylase Rattus norvegicus 33-35 27444243-0 2016 beta-asarone increases MEF2D and TH levels and reduces alpha-synuclein level in 6-OHDA-induced rats via regulating the HSP70/MAPK/MEF2D/Beclin-1 pathway: Chaperone-mediated autophagy activation, macroautophagy inhibition and HSP70 up-expression. asarone 0-12 synuclein alpha Rattus norvegicus 55-70 27444243-0 2016 beta-asarone increases MEF2D and TH levels and reduces alpha-synuclein level in 6-OHDA-induced rats via regulating the HSP70/MAPK/MEF2D/Beclin-1 pathway: Chaperone-mediated autophagy activation, macroautophagy inhibition and HSP70 up-expression. asarone 0-12 heat shock protein family A (Hsp70) member 1B Rattus norvegicus 119-124 27444243-0 2016 beta-asarone increases MEF2D and TH levels and reduces alpha-synuclein level in 6-OHDA-induced rats via regulating the HSP70/MAPK/MEF2D/Beclin-1 pathway: Chaperone-mediated autophagy activation, macroautophagy inhibition and HSP70 up-expression. asarone 0-12 myocyte enhancer factor 2D Rattus norvegicus 130-135 27444243-0 2016 beta-asarone increases MEF2D and TH levels and reduces alpha-synuclein level in 6-OHDA-induced rats via regulating the HSP70/MAPK/MEF2D/Beclin-1 pathway: Chaperone-mediated autophagy activation, macroautophagy inhibition and HSP70 up-expression. asarone 0-12 beclin 1 Rattus norvegicus 136-144 27444243-0 2016 beta-asarone increases MEF2D and TH levels and reduces alpha-synuclein level in 6-OHDA-induced rats via regulating the HSP70/MAPK/MEF2D/Beclin-1 pathway: Chaperone-mediated autophagy activation, macroautophagy inhibition and HSP70 up-expression. asarone 0-12 heat shock protein family A (Hsp70) member 1B Rattus norvegicus 225-230 27444243-0 2016 beta-asarone increases MEF2D and TH levels and reduces alpha-synuclein level in 6-OHDA-induced rats via regulating the HSP70/MAPK/MEF2D/Beclin-1 pathway: Chaperone-mediated autophagy activation, macroautophagy inhibition and HSP70 up-expression. Oxidopamine 80-86 synuclein alpha Rattus norvegicus 55-70 27444243-0 2016 beta-asarone increases MEF2D and TH levels and reduces alpha-synuclein level in 6-OHDA-induced rats via regulating the HSP70/MAPK/MEF2D/Beclin-1 pathway: Chaperone-mediated autophagy activation, macroautophagy inhibition and HSP70 up-expression. Oxidopamine 80-86 heat shock protein family A (Hsp70) member 1B Rattus norvegicus 119-124 27444243-0 2016 beta-asarone increases MEF2D and TH levels and reduces alpha-synuclein level in 6-OHDA-induced rats via regulating the HSP70/MAPK/MEF2D/Beclin-1 pathway: Chaperone-mediated autophagy activation, macroautophagy inhibition and HSP70 up-expression. Oxidopamine 80-86 myocyte enhancer factor 2D Rattus norvegicus 130-135 27444243-0 2016 beta-asarone increases MEF2D and TH levels and reduces alpha-synuclein level in 6-OHDA-induced rats via regulating the HSP70/MAPK/MEF2D/Beclin-1 pathway: Chaperone-mediated autophagy activation, macroautophagy inhibition and HSP70 up-expression. Oxidopamine 80-86 beclin 1 Rattus norvegicus 136-144 27444243-0 2016 beta-asarone increases MEF2D and TH levels and reduces alpha-synuclein level in 6-OHDA-induced rats via regulating the HSP70/MAPK/MEF2D/Beclin-1 pathway: Chaperone-mediated autophagy activation, macroautophagy inhibition and HSP70 up-expression. Oxidopamine 80-86 heat shock protein family A (Hsp70) member 1B Rattus norvegicus 225-230 27444243-3 2016 We found that beta-asarone had positive effects on treating 6-hydroxydopamine (6-OHDA)-induced rats, but mechanisms of beta-asarone affecting on MEF2D and alpha-syn via regulating the HSP70/MAPK/MEF2D/Beclin-1 pathway remain unclear. asarone 119-131 myocyte enhancer factor 2D Rattus norvegicus 145-150 27444243-3 2016 We found that beta-asarone had positive effects on treating 6-hydroxydopamine (6-OHDA)-induced rats, but mechanisms of beta-asarone affecting on MEF2D and alpha-syn via regulating the HSP70/MAPK/MEF2D/Beclin-1 pathway remain unclear. asarone 119-131 synuclein alpha Rattus norvegicus 155-164 27444243-3 2016 We found that beta-asarone had positive effects on treating 6-hydroxydopamine (6-OHDA)-induced rats, but mechanisms of beta-asarone affecting on MEF2D and alpha-syn via regulating the HSP70/MAPK/MEF2D/Beclin-1 pathway remain unclear. asarone 119-131 heat shock protein family A (Hsp70) member 1B Rattus norvegicus 184-189 27444243-3 2016 We found that beta-asarone had positive effects on treating 6-hydroxydopamine (6-OHDA)-induced rats, but mechanisms of beta-asarone affecting on MEF2D and alpha-syn via regulating the HSP70/MAPK/MEF2D/Beclin-1 pathway remain unclear. asarone 119-131 myocyte enhancer factor 2D Rattus norvegicus 195-200 27444243-3 2016 We found that beta-asarone had positive effects on treating 6-hydroxydopamine (6-OHDA)-induced rats, but mechanisms of beta-asarone affecting on MEF2D and alpha-syn via regulating the HSP70/MAPK/MEF2D/Beclin-1 pathway remain unclear. asarone 119-131 beclin 1 Rattus norvegicus 201-209 27444243-8 2016 alpha-syn, Beclin-1 and LC3B levels were higher in the 6-OHDA model group, while TH, MEF2D, HSC70, LAMP-2A, p62 levels were lower compared to the sham-operated group. Oxidopamine 55-61 synuclein alpha Rattus norvegicus 0-9 27444243-8 2016 alpha-syn, Beclin-1 and LC3B levels were higher in the 6-OHDA model group, while TH, MEF2D, HSC70, LAMP-2A, p62 levels were lower compared to the sham-operated group. Oxidopamine 55-61 beclin 1 Rattus norvegicus 11-19 27444243-9 2016 Our results also showed thatbeta-asarone treatment reduced protein and mRNA levels of alpha-syn, Beclin-1 and LC3B, but increased HSP70, TH, MEF2D, HSC70, LAMP-2A and p62 levels compared to the 6-OHDA model group. thatbeta-asarone 24-40 synuclein alpha Rattus norvegicus 86-95 27444243-9 2016 Our results also showed thatbeta-asarone treatment reduced protein and mRNA levels of alpha-syn, Beclin-1 and LC3B, but increased HSP70, TH, MEF2D, HSC70, LAMP-2A and p62 levels compared to the 6-OHDA model group. thatbeta-asarone 24-40 beclin 1 Rattus norvegicus 97-105 27444243-9 2016 Our results also showed thatbeta-asarone treatment reduced protein and mRNA levels of alpha-syn, Beclin-1 and LC3B, but increased HSP70, TH, MEF2D, HSC70, LAMP-2A and p62 levels compared to the 6-OHDA model group. thatbeta-asarone 24-40 heat shock protein family A (Hsp70) member 1B Rattus norvegicus 130-135 27444243-9 2016 Our results also showed thatbeta-asarone treatment reduced protein and mRNA levels of alpha-syn, Beclin-1 and LC3B, but increased HSP70, TH, MEF2D, HSC70, LAMP-2A and p62 levels compared to the 6-OHDA model group. thatbeta-asarone 24-40 tyrosine hydroxylase Rattus norvegicus 137-139 27444243-9 2016 Our results also showed thatbeta-asarone treatment reduced protein and mRNA levels of alpha-syn, Beclin-1 and LC3B, but increased HSP70, TH, MEF2D, HSC70, LAMP-2A and p62 levels compared to the 6-OHDA model group. thatbeta-asarone 24-40 myocyte enhancer factor 2D Rattus norvegicus 141-146 27444243-9 2016 Our results also showed thatbeta-asarone treatment reduced protein and mRNA levels of alpha-syn, Beclin-1 and LC3B, but increased HSP70, TH, MEF2D, HSC70, LAMP-2A and p62 levels compared to the 6-OHDA model group. thatbeta-asarone 24-40 heat shock protein family A (Hsp70) member 8 Rattus norvegicus 148-153 27444243-9 2016 Our results also showed thatbeta-asarone treatment reduced protein and mRNA levels of alpha-syn, Beclin-1 and LC3B, but increased HSP70, TH, MEF2D, HSC70, LAMP-2A and p62 levels compared to the 6-OHDA model group. thatbeta-asarone 24-40 KH RNA binding domain containing, signal transduction associated 1 Rattus norvegicus 167-170 27444243-11 2016 These findings suggested that beta-asarone treatment could increase MEF2D and TH as well as reduce alpha-syn to protect against 6-OHDA induced damage in PD rat mesencephalon via modulating the HSP70/MAPK/MEF2D/Beclin-1 pathway. asarone 30-42 myocyte enhancer factor 2D Rattus norvegicus 68-73 27444243-11 2016 These findings suggested that beta-asarone treatment could increase MEF2D and TH as well as reduce alpha-syn to protect against 6-OHDA induced damage in PD rat mesencephalon via modulating the HSP70/MAPK/MEF2D/Beclin-1 pathway. asarone 30-42 synuclein alpha Rattus norvegicus 99-108 27444243-11 2016 These findings suggested that beta-asarone treatment could increase MEF2D and TH as well as reduce alpha-syn to protect against 6-OHDA induced damage in PD rat mesencephalon via modulating the HSP70/MAPK/MEF2D/Beclin-1 pathway. asarone 30-42 heat shock protein family A (Hsp70) member 1B Rattus norvegicus 193-198 27444243-11 2016 These findings suggested that beta-asarone treatment could increase MEF2D and TH as well as reduce alpha-syn to protect against 6-OHDA induced damage in PD rat mesencephalon via modulating the HSP70/MAPK/MEF2D/Beclin-1 pathway. asarone 30-42 myocyte enhancer factor 2D Rattus norvegicus 204-209 27444243-11 2016 These findings suggested that beta-asarone treatment could increase MEF2D and TH as well as reduce alpha-syn to protect against 6-OHDA induced damage in PD rat mesencephalon via modulating the HSP70/MAPK/MEF2D/Beclin-1 pathway. asarone 30-42 beclin 1 Rattus norvegicus 210-218