Title : 'Rod and ring' formation from IMP dehydrogenase is regulated through the one-carbon metabolic pathway.

Pub. Date : 2016 Aug 1

PMID : 27343244






4 Functional Relationships(s)
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Protein Name
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1 We now report that depriving cells of serine and glycine promotes RR formation, and we have traced these effects to dihydrofolate reductase (DHFR) and serine hydroxymethyltransferase-2 (SHMT2), pivotal enzymes in one-carbon metabolism and nucleotide biosynthesis. Serine serine hydroxymethyltransferase 2 Homo sapiens
2 We now report that depriving cells of serine and glycine promotes RR formation, and we have traced these effects to dihydrofolate reductase (DHFR) and serine hydroxymethyltransferase-2 (SHMT2), pivotal enzymes in one-carbon metabolism and nucleotide biosynthesis. Serine serine hydroxymethyltransferase 2 Homo sapiens
3 We now report that depriving cells of serine and glycine promotes RR formation, and we have traced these effects to dihydrofolate reductase (DHFR) and serine hydroxymethyltransferase-2 (SHMT2), pivotal enzymes in one-carbon metabolism and nucleotide biosynthesis. Carbon serine hydroxymethyltransferase 2 Homo sapiens
4 We now report that depriving cells of serine and glycine promotes RR formation, and we have traced these effects to dihydrofolate reductase (DHFR) and serine hydroxymethyltransferase-2 (SHMT2), pivotal enzymes in one-carbon metabolism and nucleotide biosynthesis. Carbon serine hydroxymethyltransferase 2 Homo sapiens