Title : Melatonin regulates catecholamine biosynthesis by modulating bone morphogenetic protein and glucocorticoid actions.

Pub. Date : 2017 Jan

PMID : 27267863






1 Functional Relationships(s)
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1 Of note, melatonin significantly upregulated Alk2 and Bmpr2 mRNA levels but suppressed inhibitory Smad6/7 expression, leading to the enhancement of SMAD1/5/8 signaling in PC12 cells, while BMP-4 did not affect Mt1 expression. Melatonin bone morphogenetic protein receptor type 2 Rattus norvegicus