Title : Low density lipoprotein metabolism in rats with puromycin aminonucleoside-induced nephrotic syndrome.

Pub. Date : 1989 May

PMID : 2725289






1 Functional Relationships(s)
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1 Apolipoprotein B (apo B) kinetic measurements using homologous 125I-labeled low density lipoproteins (LDL) demonstrated a higher synthetic rate in nephrotic rats relative to controls (6.18 +/- 1.86 micrograms x g-1 x d-1 v 3.94 +/- 0.66 micrograms x g-1 x d-1 respectively, P less than .005), while the fractional catabolic rate was only marginally reduced (1.64 +/- 0.28 pools x day-1 in NS v 1.83 +/- 0.37 pools x day-1 in controls, P less than 0.4). Iodine-125 apolipoprotein B Rattus norvegicus