Title : Mutations in the 'Fingers' subdomain of the deubiquitinase USP1 modulate its function and activity.

Pub. Date : 2016 Mar

PMID : 26758085






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Small interfering RNA-mediated USP1 knockdown or treatment with the novel USP1-UAF1 inhibitor ML323 increased the recruitment of conjugated ubiquitin and 53BP1 into nuclear foci. ML323 ubiquitin specific peptidase 1 Homo sapiens
2 Small interfering RNA-mediated USP1 knockdown or treatment with the novel USP1-UAF1 inhibitor ML323 increased the recruitment of conjugated ubiquitin and 53BP1 into nuclear foci. ML323 WD repeat domain 48 Homo sapiens
3 Small interfering RNA-mediated USP1 knockdown or treatment with the novel USP1-UAF1 inhibitor ML323 increased the recruitment of conjugated ubiquitin and 53BP1 into nuclear foci. ML323 tumor protein p53 binding protein 1 Homo sapiens