Title : Plasmid pORF-hTRAIL targeting to glioma using transferrin-modified polyamidoamine dendrimer.

Pub. Date : 2016

PMID : 26719669






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Gene drug, tumor necrosis factor-related apoptosis-inducing ligand (hTRAIL)-encoding plasmid open reading frame (pORF-hTRAIL, Trail), was condensed by Tf-modified PAMAM to form nanoparticles (NPs). pamam TNF superfamily member 10 Rattus norvegicus
2 The median survival time of PAMAM-PEG-Tf/Trail-treated rats (28.5 days) was longer than that of rats treated with PAMAM-PEG/Trail (25.5 days), temozolomide (24.5 days), PAMAM-PEG-Tf/pEGFP (19 days), or saline (17 days). pamam-peg-tf TNF superfamily member 10 Rattus norvegicus
3 The median survival time of PAMAM-PEG-Tf/Trail-treated rats (28.5 days) was longer than that of rats treated with PAMAM-PEG/Trail (25.5 days), temozolomide (24.5 days), PAMAM-PEG-Tf/pEGFP (19 days), or saline (17 days). pamam-peg TNF superfamily member 10 Rattus norvegicus