Title : Inactivation of ANGPTL3 reduces hepatic VLDL-triglyceride secretion.

Pub. Date : 2015 Jul

PMID : 25954050






4 Functional Relationships(s)
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1 Inactivation of ANGPTL3 reduces hepatic VLDL-triglyceride secretion. Triglycerides angiopoietin-like 3 Mus musculus
2 ANGPTL3 inhibits two intravascular lipases, LPL and endothelial lipase, and the low plasma TG and HDL-cholesterol levels in ANGPTL3 deficiency reflect increased activity of these enzymes. Thioguanine angiopoietin-like 3 Mus musculus
3 ANGPTL3 inhibits two intravascular lipases, LPL and endothelial lipase, and the low plasma TG and HDL-cholesterol levels in ANGPTL3 deficiency reflect increased activity of these enzymes. Cholesterol angiopoietin-like 3 Mus musculus
4 The mechanism responsible for the low LDL-cholesterol levels associated with ANGPTL3 deficiency is not known. Cholesterol angiopoietin-like 3 Mus musculus