Title : Effects of chlordecone administration on brain and pituitary peptide systems.

Pub. Date : 1985 Spring

PMID : 2581193






3 Functional Relationships(s)
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1 Similarly, chlordecone treatment reduced the pituitary content of enkephalin in a manner identical to that of estrogen. Chlordecone proenkephalin Rattus norvegicus
2 Moreover, due to the similarity of both estrogen and chlordecone to anti-dopaminergic agents in altering [Met5]-enkephalin levels in both the pituitary and caudate nucleus it is speculated that a dopaminergic mechanism is responsible for their actions on the enkephalin system. Chlordecone proenkephalin Rattus norvegicus
3 Moreover, due to the similarity of both estrogen and chlordecone to anti-dopaminergic agents in altering [Met5]-enkephalin levels in both the pituitary and caudate nucleus it is speculated that a dopaminergic mechanism is responsible for their actions on the enkephalin system. Chlordecone proenkephalin Rattus norvegicus