Pub. Date : 2015 Apr 17
PMID : 25759388
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Using membranes prepared from adult rat cardiac myocytes and fibroblasts, we found that MMP14 activity is increased by angiotensin II, phenylephrine, GTP, and guanosine 5"-O-[gamma-thio]triphosphate (GTPgammaS). | Phenylephrine | matrix metallopeptidase 14 | Rattus norvegicus |
| 2 | Using membranes prepared from adult rat cardiac myocytes and fibroblasts, we found that MMP14 activity is increased by angiotensin II, phenylephrine, GTP, and guanosine 5"-O-[gamma-thio]triphosphate (GTPgammaS). | Guanosine Triphosphate | matrix metallopeptidase 14 | Rattus norvegicus |
| 3 | Using membranes prepared from adult rat cardiac myocytes and fibroblasts, we found that MMP14 activity is increased by angiotensin II, phenylephrine, GTP, and guanosine 5"-O-[gamma-thio]triphosphate (GTPgammaS). | guanosine 5"-o-[gamma-thio]triphosphate | matrix metallopeptidase 14 | Rattus norvegicus |
| 4 | Using membranes prepared from adult rat cardiac myocytes and fibroblasts, we found that MMP14 activity is increased by angiotensin II, phenylephrine, GTP, and guanosine 5"-O-[gamma-thio]triphosphate (GTPgammaS). | GTPgammaS | matrix metallopeptidase 14 | Rattus norvegicus |
| 5 | MMP14 activation by GTPgammaS occurs in a concentration- and time-dependent manner, does not occur in response to GMP or adenosine 5"-[gamma-thio]triphosphate (ATPgammaS), and is not blunted by inhibitors of Src, PKC, phospholipase C (PLC), PI3K, or soluble MMPs. | GTPgammaS | matrix metallopeptidase 14 | Rattus norvegicus |
| 6 | MMP14 activation by GTPgammaS occurs in a concentration- and time-dependent manner, does not occur in response to GMP or adenosine 5"-[gamma-thio]triphosphate (ATPgammaS), and is not blunted by inhibitors of Src, PKC, phospholipase C (PLC), PI3K, or soluble MMPs. | GTPgammaS | matrix metallopeptidase 14 | Rattus norvegicus |
| 7 | MMP14 activation by GTPgammaS occurs in a concentration- and time-dependent manner, does not occur in response to GMP or adenosine 5"-[gamma-thio]triphosphate (ATPgammaS), and is not blunted by inhibitors of Src, PKC, phospholipase C (PLC), PI3K, or soluble MMPs. | adenosine 5'-O-(3-thiotriphosphate) | matrix metallopeptidase 14 | Rattus norvegicus |
| 8 | GTPgammaS-stimulated activation of MMP14 also results in membrane release of HB-EGF and the activation of EGFR. | GTPgammaS | matrix metallopeptidase 14 | Rattus norvegicus |