Title : Structure of the Elongator cofactor complex Kti11/Kti13 provides insight into the role of Kti13 in Elongator-dependent tRNA modification.

Pub. Date : 2015 Mar

PMID : 25604895






5 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Kti11 was additionally shown to be implicated in the biosynthesis of diphthamide, a post-translationally modified histidine of translation elongation factor 2. diphthamide diphthamide biosynthesis 3 Homo sapiens
2 Kti11 was additionally shown to be implicated in the biosynthesis of diphthamide, a post-translationally modified histidine of translation elongation factor 2. Histidine diphthamide biosynthesis 3 Homo sapiens
3 Recent data indicate that iron-bearing Kti11 functions as an electron donor to the [4Fe-4S] cluster of radical S-Adenosylmethionine enzymes, triggering the subsequent radical reaction. Iron diphthamide biosynthesis 3 Homo sapiens
4 In the complex, Kti13 orients Kti11 and restricts access to its electron-carrying iron atom, constraining the electron transfer capacity of Kti11. Iron diphthamide biosynthesis 3 Homo sapiens
5 In the complex, Kti13 orients Kti11 and restricts access to its electron-carrying iron atom, constraining the electron transfer capacity of Kti11. Iron diphthamide biosynthesis 3 Homo sapiens