Title : Mechanism-based inhibitory and peroxisome proliferator-activated receptor α-dependent modulating effects of silybin on principal hepatic drug-metabolizing enzymes.

Pub. Date : 2015 Apr

PMID : 25587127






1 Functional Relationships(s)
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1 However, silybin could significantly compromise the activation of PPARalpha by fenofibrate, characterized with significantly repressed expression of PPARalpha targeting genes, including L-FABP, ACOX1, and UGT1A6. Silybin acyl-Coenzyme A oxidase 1, palmitoyl Mus musculus