Protein Name acyl-Coenzyme A oxidase 1, palmitoyl
Organism Mus musculus
Gene ID 11430
Gene Symbol


UniProt Q9R0H0 (ACOX1_MOUSE)
Relationships Total Number of functionally related compound(s) : 118
Total Number of Articles : 96

acyl-Coenzyme A oxidase 1, palmitoyl

Gene Summary

This gene encodes a member of the acyl-coenzyme A oxidase family. The encoded protein is localized to peroxisomes and is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-coenzyme A to 2-trans-enoyl-coenzyme A. Disruption of this gene results in microvesicular steatohepatitis, spontaneous peroxisome proliferation, and the eventual development of hepatocellular carcinomas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]

  • peroxisomal acyl-coenzyme A oxidase 1
  • palmitoyl-CoA oxidase
  • peroxisomal fatty acyl-CoA oxidase
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