Pub. Date : 1989 Aug 22
PMID : 2554959
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The association constants for the formation of CRP-cAMP and CRP-(cAMP)2 complexes derived from conformational studies are in good agreement with those determined by equilibrium dialysis, nonequilibrium dialysis, and ultrafiltration. | Cyclic AMP | catabolite gene activator protein | Escherichia coli |
| 2 | Therefore, the simplest explanation would be that the protein exhibits three conformational states, free CRP and two cAMP-dependent states, which correspond to the CRP-cAMP and CRP-(cAMP)2 complexes. | Cyclic AMP | catabolite gene activator protein | Escherichia coli |
| 3 | Therefore, the simplest explanation would be that the protein exhibits three conformational states, free CRP and two cAMP-dependent states, which correspond to the CRP-cAMP and CRP-(cAMP)2 complexes. | Cyclic AMP | catabolite gene activator protein | Escherichia coli |
| 4 | Therefore, the simplest explanation would be that the protein exhibits three conformational states, free CRP and two cAMP-dependent states, which correspond to the CRP-cAMP and CRP-(cAMP)2 complexes. | Cyclic AMP | catabolite gene activator protein | Escherichia coli |
| 5 | At a high concentration of cAMP which favors the formation of the CRP-(cAMP)2 complex, binding of the protein to DNA is decreased. | Cyclic AMP | catabolite gene activator protein | Escherichia coli |
| 6 | This, together with conformational data, strongly suggests that only the CRP-cAMP complex is active in specific DNA binding whereas CRP and CRP-(cAMP)2 are not. | Cyclic AMP | catabolite gene activator protein | Escherichia coli |