Title : MicroRNA-130b regulates scleroderma fibrosis by targeting peroxisome proliferator-activated receptor γ.

Pub. Date : 2015 Jul

PMID : 25547017






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Cells were transfected with microRNA mimics/inhibitor/scramble of miR-130b using Lipofectamine. Lipofectamine microRNA 130b Homo sapiens
2 Similar to human SSc, the same expression patterns of miR-130b, PPARgamma, and fibrosis-related genes were observed in the bleomycin-induced skin fibrosis model; TGF-beta induced the expression of miR-130b and fibrosis-related genes expression, but downregulated the expression of PPARgamma. Bleomycin microRNA 130b Homo sapiens
3 Similar to human SSc, the same expression patterns of miR-130b, PPARgamma, and fibrosis-related genes were observed in the bleomycin-induced skin fibrosis model; TGF-beta induced the expression of miR-130b and fibrosis-related genes expression, but downregulated the expression of PPARgamma. Bleomycin microRNA 130b Homo sapiens