Pub. Date : 2015 Jan 5
PMID : 25449038
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Hinokitiol appeared to achieve this effect by reducing the expression of MMP-1 and by suppressing the phosphorylation of mitogen- activated protein kinase (MAPK) signaling molecules such as extracellular signal-regulated kinase (ERK) 1/2, p38 MAPK and c-Jun N-terminal kinases (JNK). | beta-thujaplicin | matrix metallopeptidase 13 | Mus musculus |
| 2 | Hinokitiol appeared to achieve this effect by reducing the expression of MMP-1 and by suppressing the phosphorylation of mitogen- activated protein kinase (MAPK) signaling molecules such as extracellular signal-regulated kinase (ERK) 1/2, p38 MAPK and c-Jun N-terminal kinases (JNK). | beta-thujaplicin | mitogen-activated protein kinase 1 | Mus musculus |
| 3 | Hinokitiol appeared to achieve this effect by reducing the expression of MMP-1 and by suppressing the phosphorylation of mitogen- activated protein kinase (MAPK) signaling molecules such as extracellular signal-regulated kinase (ERK) 1/2, p38 MAPK and c-Jun N-terminal kinases (JNK). | beta-thujaplicin | mitogen-activated protein kinase 3 | Mus musculus |
| 4 | Hinokitiol appeared to achieve this effect by reducing the expression of MMP-1 and by suppressing the phosphorylation of mitogen- activated protein kinase (MAPK) signaling molecules such as extracellular signal-regulated kinase (ERK) 1/2, p38 MAPK and c-Jun N-terminal kinases (JNK). | beta-thujaplicin | mitogen-activated protein kinase 14 | Mus musculus |
| 5 | Hinokitiol appeared to achieve this effect by reducing the expression of MMP-1 and by suppressing the phosphorylation of mitogen- activated protein kinase (MAPK) signaling molecules such as extracellular signal-regulated kinase (ERK) 1/2, p38 MAPK and c-Jun N-terminal kinases (JNK). | beta-thujaplicin | jun proto-oncogene | Mus musculus |
| 6 | On the other hand, hinokitiol treatment reversed IkappaB-alpha degradation and inhibited the phosphorylation of p65 nuclear factor kappa B (NF-kappaB) and cJun in B16-F10 cells. | beta-thujaplicin | nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha | Mus musculus |
| 7 | On the other hand, hinokitiol treatment reversed IkappaB-alpha degradation and inhibited the phosphorylation of p65 nuclear factor kappa B (NF-kappaB) and cJun in B16-F10 cells. | beta-thujaplicin | jun proto-oncogene | Mus musculus |
| 8 | In addition, hinokitiol suppressed the translocation of p65 NF-kappaB from the cytosol to the nucleus, suggesting reduced NF-kappaB activation. | beta-thujaplicin | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | Mus musculus |