Pub. Date : 2015 Apr
PMID : 25245076
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Mice were superovulated and orally treated with 7.5 mg cilostazol (CLZ), a phosphodiesterase 3A (PDE3A) inhibitor, to induce ovulation of immature oocytes at different stages depending on frequency and time of administration of CLZ. | Cilostazol | phosphodiesterase 3A, cGMP inhibited | Mus musculus |
| 2 | Mice were superovulated and orally treated with 7.5 mg cilostazol (CLZ), a phosphodiesterase 3A (PDE3A) inhibitor, to induce ovulation of immature oocytes at different stages depending on frequency and time of administration of CLZ. | Cilostazol | phosphodiesterase 3A, cGMP inhibited | Mus musculus |
| 3 | Mice were superovulated and orally treated with 7.5 mg cilostazol (CLZ), a phosphodiesterase 3A (PDE3A) inhibitor, to induce ovulation of immature oocytes at different stages depending on frequency and time of administration of CLZ. | Cilostazol | phosphodiesterase 3A, cGMP inhibited | Mus musculus |
| 4 | The capability of a clinically approved PDE3A inhibitor to improve oocyte fertilization rates in mice at doses extrapolated from human therapeutic doses suggests the potential scenario of the inclusion of CLZ in superovulation programs. | Cilostazol | phosphodiesterase 3A, cGMP inhibited | Mus musculus |