Title : Regulation of hypoxia-inducible factor-α isoforms and redox state by carotid body neural activity in rats.

Pub. Date : 2014 Sep 1

PMID : 24973414






1 Functional Relationships(s)
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1 Rats exposed to CIH exhibited: increased HIF-1alpha and decreased HIF-2alpha expression; increased NADPH oxidase 2 and decreased superoxide dismutase 2 expression; and oxidative stress in the nucleus tractus solitarius and rostral ventrolateral medulla as well as in the adrenal medulla (AM), a major end organ of the sympathetic nervous system. cih endothelial PAS domain protein 1 Rattus norvegicus