Title : Oral cancer cells may rewire alternative metabolic pathways to survive from siRNA silencing of metabolic enzymes.

Pub. Date : 2014 Mar 25

PMID : 24666435






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We also demonstrated that siRNA knockdown of AK2 constrained the proliferation of UM1 and UM2 cells but similarly led to an increased uptake of glucose/glutamine and production of lactate by the UM1 or UM2 cells survived from siRNA silencing of AK2. Glucose adenylate kinase 2 Homo sapiens
2 We also demonstrated that siRNA knockdown of AK2 constrained the proliferation of UM1 and UM2 cells but similarly led to an increased uptake of glucose/glutamine and production of lactate by the UM1 or UM2 cells survived from siRNA silencing of AK2. Glutamine adenylate kinase 2 Homo sapiens
3 We also demonstrated that siRNA knockdown of AK2 constrained the proliferation of UM1 and UM2 cells but similarly led to an increased uptake of glucose/glutamine and production of lactate by the UM1 or UM2 cells survived from siRNA silencing of AK2. Lactic Acid adenylate kinase 2 Homo sapiens