Pub. Date : 2014 May 7
PMID : 24643241
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here we present the first QM/MM calculations of human GalNAc-T2, a retaining glycosyltransferase, which initiates the biosynthesis of mucin-type O-glycans. | o-glycans | polypeptide N-acetylgalactosaminyltransferase 2 | Homo sapiens |
| 2 | Additionally, our calculations for different donor substrates suggest that human GalNAc-T2 would be inactive if 2"-deoxy-Gal or 2"-oxymethyl-Gal were used, while UDP-Gal is confirmed as a valid sugar donor. | 2"-deoxy-gal | polypeptide N-acetylgalactosaminyltransferase 2 | Homo sapiens |
| 3 | Additionally, our calculations for different donor substrates suggest that human GalNAc-T2 would be inactive if 2"-deoxy-Gal or 2"-oxymethyl-Gal were used, while UDP-Gal is confirmed as a valid sugar donor. | 2"-oxymethyl-gal | polypeptide N-acetylgalactosaminyltransferase 2 | Homo sapiens |
| 4 | Additionally, our calculations for different donor substrates suggest that human GalNAc-T2 would be inactive if 2"-deoxy-Gal or 2"-oxymethyl-Gal were used, while UDP-Gal is confirmed as a valid sugar donor. | Sugars | polypeptide N-acetylgalactosaminyltransferase 2 | Homo sapiens |