PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24643241-3	2014	Here we present the first QM/MM calculations of human GalNAc-T2, a retaining glycosyltransferase, which initiates the biosynthesis of mucin-type O-glycans.	o-glycans	145-154	polypeptide N-acetylgalactosaminyltransferase 2	Homo sapiens	54-63	
24643241-4	2014	Importantly, we have characterized a hydrogen bond between the beta-phosphate of UDP and the backbone amide group from the Thr7 of the sugar acceptor (EA2 peptide) that promotes catalysis and that we propose could be a general catalytic strategy used in peptide O-glycosylation by retaining glycosyltransferases.	Hydrogen	37-45	calcium voltage-gated channel subunit alpha1 A	Homo sapiens	151-154	
24643241-4	2014	Importantly, we have characterized a hydrogen bond between the beta-phosphate of UDP and the backbone amide group from the Thr7 of the sugar acceptor (EA2 peptide) that promotes catalysis and that we propose could be a general catalytic strategy used in peptide O-glycosylation by retaining glycosyltransferases.	beta-phosphate	63-77	calcium voltage-gated channel subunit alpha1 A	Homo sapiens	151-154	
24643241-4	2014	Importantly, we have characterized a hydrogen bond between the beta-phosphate of UDP and the backbone amide group from the Thr7 of the sugar acceptor (EA2 peptide) that promotes catalysis and that we propose could be a general catalytic strategy used in peptide O-glycosylation by retaining glycosyltransferases.	Uridine Diphosphate	81-84	calcium voltage-gated channel subunit alpha1 A	Homo sapiens	151-154	
24643241-4	2014	Importantly, we have characterized a hydrogen bond between the beta-phosphate of UDP and the backbone amide group from the Thr7 of the sugar acceptor (EA2 peptide) that promotes catalysis and that we propose could be a general catalytic strategy used in peptide O-glycosylation by retaining glycosyltransferases.	Amides	102-107	calcium voltage-gated channel subunit alpha1 A	Homo sapiens	151-154	
24643241-4	2014	Importantly, we have characterized a hydrogen bond between the beta-phosphate of UDP and the backbone amide group from the Thr7 of the sugar acceptor (EA2 peptide) that promotes catalysis and that we propose could be a general catalytic strategy used in peptide O-glycosylation by retaining glycosyltransferases.	Sugars	135-140	calcium voltage-gated channel subunit alpha1 A	Homo sapiens	151-154	
24643241-8	2014	Additionally, our calculations for different donor substrates suggest that human GalNAc-T2 would be inactive if 2"-deoxy-Gal or 2"-oxymethyl-Gal were used, while UDP-Gal is confirmed as a valid sugar donor.	2"-deoxy-gal	112-124	polypeptide N-acetylgalactosaminyltransferase 2	Homo sapiens	81-90	
24643241-8	2014	Additionally, our calculations for different donor substrates suggest that human GalNAc-T2 would be inactive if 2"-deoxy-Gal or 2"-oxymethyl-Gal were used, while UDP-Gal is confirmed as a valid sugar donor.	2"-oxymethyl-gal	128-144	polypeptide N-acetylgalactosaminyltransferase 2	Homo sapiens	81-90	
24643241-8	2014	Additionally, our calculations for different donor substrates suggest that human GalNAc-T2 would be inactive if 2"-deoxy-Gal or 2"-oxymethyl-Gal were used, while UDP-Gal is confirmed as a valid sugar donor.	Sugars	194-199	polypeptide N-acetylgalactosaminyltransferase 2	Homo sapiens	81-90