Title : Targeting annexin A7 by a small molecule suppressed the activity of phosphatidylcholine-specific phospholipase C in vascular endothelial cells and inhibited atherosclerosis in apolipoprotein E⁻/⁻mice.

Pub. Date : 2013 Sep 19

PMID : 24052074






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Targeting annexin A7 by a small molecule suppressed the activity of phosphatidylcholine-specific phospholipase C in vascular endothelial cells and inhibited atherosclerosis in apolipoprotein E-/-mice. Phosphatidylcholines annexin A7 Mus musculus
2 We recently found a small chemical molecule (6-amino-2, 3-dihydro-3-hydroxymethyl-1, 4-benzoxazine, ABO) that could inhibit oxidized low-density lipoprotein (oxLDL)-induced apoptosis and promote autophagy in VECs, and further identified ABO as an inhibitor of annexin A7 (ANXA7) GTPase. 6-amino-2,3-dihydro-3-hydroxymethyl-1,4-benzoxazine annexin A7 Mus musculus
3 We recently found a small chemical molecule (6-amino-2, 3-dihydro-3-hydroxymethyl-1, 4-benzoxazine, ABO) that could inhibit oxidized low-density lipoprotein (oxLDL)-induced apoptosis and promote autophagy in VECs, and further identified ABO as an inhibitor of annexin A7 (ANXA7) GTPase. 6-amino-2,3-dihydro-3-hydroxymethyl-1,4-benzoxazine annexin A7 Mus musculus