Pub. Date : 1990 May
PMID : 2393963
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Western blotting analysis showed a marked decrease in the male-specific cytochrome P450 UT-2 in the hepatic microsomes, especially 24 to 48 h after pretreatment with CBD. | Cannabidiol | cytochrome P450, subfamily 2, polypeptide 11 | Rattus norvegicus |
| 2 | In the later stages from 24 to 48 h after CBD treatment, the reduction in content of the male-specific cytochrome P450 UT-2 may play a major role in the inhibitory effect of CBD on the hepatic drug-metabolizing enzyme system in the adult male rat in vivo. | Cannabidiol | cytochrome P450, subfamily 2, polypeptide 11 | Rattus norvegicus |