Title : Gab docking proteins in cardiovascular disease, cancer, and inflammation.

Pub. Date : 2013

PMID : 23431498






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Gab proteins lack the enzymatic activity themselves; however, when phosphorylated on tyrosine residues, they provide binding sites for multiple Src homology-2 (SH2) domain-containing proteins, such as SH2-containing protein tyrosine phosphatase 2 (SHP2), phosphatidylinositol 3-kinase regulatory subunit p85, phospholipase Cgamma, Crk, and GC-GAP. Tyrosine Rho GTPase activating protein 32 Homo sapiens