Pub. Date : 2013 May
PMID : 23402856
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Number and area of preneoplastic foci positive for glutathione S-transferase placental form (GST-P) were consistently higher in these groups than the sum of individual values in the groups treated with HEP or HCB alone. | Heptachlor | glutathione S-transferase pi 1 | Rattus norvegicus |
2 | Consistent with these findings, HEP and HCB had additive or synergistic effects on cell proliferation induction within the preneoplastic foci and cytochrome P450 (CYP) 2B1 and 3A1 induction, which may lead to more efficient metabolic activation of HEP and HCB. | Heptachlor | cytochrome P450 2B1 | Rattus norvegicus |