| Protein Name | glutathione S-transferase pi 1 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 24426 |
| Gene Symbol | Gstp1 |
| UniProt | P04906 (GSTP1_RAT), B6DYQ7 (B6DYQ7_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
336
Total Number of Articles : 391 |
Description |
glutathione S-transferase pi 1 |
| Gene Summary |
Enables protein kinase binding activity and toxic substance binding activity. Involved in several processes, including cellular response to cell-matrix adhesion; cellular response to epidermal growth factor stimulus; and negative regulation of smooth muscle cell chemotaxis. Predicted to be located in mitochondrion. Predicted to be part of TRAF2-GSTP1 complex. Predicted to be active in cytosol. Biomarker of cholestasis; pre-malignant neoplasm; prostate carcinoma in situ; prostatic hypertrophy; and urinary bladder cancer. Human ortholog(s) of this gene implicated in several diseases, including allergic disease (multiple); carcinoma (multiple); hematologic cancer (multiple); reproductive organ cancer (multiple); and respiratory system disease (multiple). Orthologous to human GSTP1 (glutathione S-transferase pi 1). [provided by Alliance of Genome Resources, Jun 2025] |
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