Pub. Date : 2013 Feb 28
PMID : 23395963
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Bimatoprost protects retinal neuronal damage via Akt pathway. | Bimatoprost | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | To elucidate the protective mechanism of bimatoprost, we used western blot analysis to investigate the phosphorylation of Akt and extracellular signal-regulated kinase (ERK). | Bimatoprost | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | To elucidate the protective mechanism of bimatoprost, we used western blot analysis to investigate the phosphorylation of Akt and extracellular signal-regulated kinase (ERK). | Bimatoprost | mitogen-activated protein kinase 1 | Homo sapiens |
| 4 | Bimatoprost induced activation of Akt and ERK, and a phosphatidylinositol 3-kinase inhibitor, LY294002, attenuated the protective effect of bimatoprost. | Bimatoprost | AKT serine/threonine kinase 1 | Homo sapiens |
| 5 | Bimatoprost induced activation of Akt and ERK, and a phosphatidylinositol 3-kinase inhibitor, LY294002, attenuated the protective effect of bimatoprost. | Bimatoprost | mitogen-activated protein kinase 1 | Homo sapiens |
| 6 | Taken together, these findings indicate that bimatoprost has protective effects on in vitro and in vivo retinal damage, suggesting that the mechanism underlying may be via the Akt pathway, which may modulate the ERK pathway. | Bimatoprost | AKT serine/threonine kinase 1 | Homo sapiens |
| 7 | Taken together, these findings indicate that bimatoprost has protective effects on in vitro and in vivo retinal damage, suggesting that the mechanism underlying may be via the Akt pathway, which may modulate the ERK pathway. | Bimatoprost | mitogen-activated protein kinase 1 | Homo sapiens |