Title : The combined expression of Pdx1 and MafA with either Ngn3 or NeuroD improves the differentiation efficiency of mouse embryonic stem cells into insulin-producing cells.

Pub. Date : 2013

PMID : 22776709






1 Functional Relationships(s)
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1 For the first time, we have demonstrated that the coexpression of Pdx1 and MafA during a specific time window of development can act synergistically with either Ngn3 or NeuroD to promote the differentiation of mES cells into insulin-secreting cells. 2-(N-morpholino)ethanesulfonic acid neurogenic differentiation 1 Mus musculus