Title : Cardiomyocyte specific deficiency of serine palmitoyltransferase subunit 2 reduces ceramide but leads to cardiac dysfunction.

Pub. Date : 2012 May 25

PMID : 22493506






1 Functional Relationships(s)
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1 Heart-specific Sptlc2-deficient (hSptlc2 KO) mice had a >35% reduction in ceramide, which was limited to C18:0 and very long chain ceramides. Ceramides serine palmitoyltransferase long chain base subunit 2 Homo sapiens