Title : Functional studies of nonpeptide angiotensin II receptor subtype-specific ligands: DuP 753 (AII-1) and PD123177 (AII-2).

Pub. Date : 1990 Nov

PMID : 2243344






7 Functional Relationships(s)
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1 DuP 753 and PD123177 are two nonpeptide angiotensin II (AII)-specific ligands, which show high affinities for two respective and distinct subtypes of AII binding sites, i.e., AII-1 and AII-2 sites, respectively, in the rat adrenal gland, brain and uterus. PD 123177 angiotensinogen Rattus norvegicus
2 DuP 753 and PD123177 are two nonpeptide angiotensin II (AII)-specific ligands, which show high affinities for two respective and distinct subtypes of AII binding sites, i.e., AII-1 and AII-2 sites, respectively, in the rat adrenal gland, brain and uterus. PD 123177 angiotensinogen Rattus norvegicus
3 DuP 753 and PD123177 are two nonpeptide angiotensin II (AII)-specific ligands, which show high affinities for two respective and distinct subtypes of AII binding sites, i.e., AII-1 and AII-2 sites, respectively, in the rat adrenal gland, brain and uterus. PD 123177 angiotensinogen Rattus norvegicus
4 DuP 753 and PD123177 are two nonpeptide angiotensin II (AII)-specific ligands, which show high affinities for two respective and distinct subtypes of AII binding sites, i.e., AII-1 and AII-2 sites, respectively, in the rat adrenal gland, brain and uterus. PD 123177 angiotensinogen Rattus norvegicus
5 DuP 753 and PD123177 are two nonpeptide angiotensin II (AII)-specific ligands, which show high affinities for two respective and distinct subtypes of AII binding sites, i.e., AII-1 and AII-2 sites, respectively, in the rat adrenal gland, brain and uterus. PD 123177 angiotensinogen Rattus norvegicus
6 In summary, a function of the PD123177-sensitive AII binding site (AII-2) has not yet been identified. PD 123177 angiotensinogen Rattus norvegicus
7 In summary, a function of the PD123177-sensitive AII binding site (AII-2) has not yet been identified. PD 123177 angiotensinogen Rattus norvegicus