Pub. Date : 2011 Dec 1
PMID : 21990321
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Mechanistic investigations revealed that the status of the O-glycans attached to the EGFR was altered by GALNT2, changing EGFR responses after EGF binding. | o-glycans | polypeptide N-acetylgalactosaminyltransferase 2 | Homo sapiens |
| 2 | Inhibiting EGFR activity with erlotinib decreased the malignant characters caused by siRNA-mediated knockdown of GALNT2 in HCC cells, establishing the critical role of EGFR in mediating the effects of GALNT2 expression. | Erlotinib Hydrochloride | polypeptide N-acetylgalactosaminyltransferase 2 | Homo sapiens |
| 3 | Inhibiting EGFR activity with erlotinib decreased the malignant characters caused by siRNA-mediated knockdown of GALNT2 in HCC cells, establishing the critical role of EGFR in mediating the effects of GALNT2 expression. | Erlotinib Hydrochloride | polypeptide N-acetylgalactosaminyltransferase 2 | Homo sapiens |