Title : 3,5-bis(2,4-difluorobenzylidene)-4-piperidone, a novel compound that affects pancreatic cancer growth and angiogenesis.

Pub. Date : 2011 Nov

PMID : 21890747






1 Functional Relationships(s)
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1 We further determined that the reduced Notch-1 activation was due to reduction in the ligand Jagged-1 and two critical components of the gamma-secretase enzyme complex presenilin-1 and nicastrin. nicastrin jagged canonical Notch ligand 1 Homo sapiens