| Protein Name | jagged canonical Notch ligand 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 182 |
| Gene Symbol | JAG1 |
| UniProt | P78504 (JAG1_HUMAN), Q99740 (Q99740_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
199
Total Number of Articles : 197 |
Description |
jagged canonical Notch ligand 1 |
| Gene Summary |
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter is involved in signaling processes. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Nov 2019] |
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