Title : [Inhibitory effect and mechanism of (-)-epigallocatechin-3-gallate on HT29 and HCT-8 colorectal cancer cell lines and expression of HES1 and JAG1].

Pub. Date : 2011 Aug

PMID : 21866461






4 Functional Relationships(s)
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1 [Inhibitory effect and mechanism of (-)-epigallocatechin-3-gallate on HT29 and HCT-8 colorectal cancer cell lines and expression of HES1 and JAG1]. epigallocatechin gallate jagged canonical Notch ligand 1 Homo sapiens
2 OBJECTIVE: To study the inhibitory effect of (-)-epigallocatechin-3-gallate (EGCG) on cancer cells line HCT-8 and HT29 and its influence on the expression of HES1 and JAG1. epigallocatechin gallate jagged canonical Notch ligand 1 Homo sapiens
3 OBJECTIVE: To study the inhibitory effect of (-)-epigallocatechin-3-gallate (EGCG) on cancer cells line HCT-8 and HT29 and its influence on the expression of HES1 and JAG1. epigallocatechin gallate jagged canonical Notch ligand 1 Homo sapiens
4 EGCG upregulated JAG1 gene expression in both cell lines, however only the difference in HCT-8 was statistically significant(0.201+-0.018 vs. 0.440+-0.077, P=0.029). epigallocatechin gallate jagged canonical Notch ligand 1 Homo sapiens