Title : Prevention of insulin-dependent diabetes mellitus in non-obese diabetic mice by transgenes encoding modified I-A beta-chain or normal I-E alpha-chain.

Pub. Date : 1990 Jun 21

PMID : 2163026






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The NOD mouse does not express I-E owing to a deletion in the promoter region of the I-E alpha-chain gene, and the sequence of NOD I-A beta-chain in the first external domain is unique with His 56 and Ser 57 replacing Pro and Asp, respectively, at these positions. Histidine histocompatibility 2, class II antigen A, beta 1 Mus musculus