CPRiL

H2-Ab1

histocompatibility 2, class II antigen A, beta 1

Enables peptide antigen binding activity. Acts upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class II and immune response. Located in Golgi apparatus; endosome; and external side of plasma membrane. Part of MHC class II protein complex. Is expressed in several structures, including adipose tissue; bone; hemolymphoid system; liver; and lung. Used to study dilated cardiomyopathy and myocarditis. Human ortholog(s) of this gene implicated in several diseases, including allergic disease (multiple); autoimmune disease (multiple); bacterial infectious disease (multiple); hematologic cancer (multiple); and liver disease (multiple). Orthologous to several human genes including HLA-DQB1 (major histocompatibility complex, class II, DQ beta 1). [provided by Alliance of Genome Resources, Jun 2025]

• histocompatibility 2, class II antigen A, beta 1
• H-2 class II histocompatibility antigen, A beta chain
• MHC class II H2-IA-beta-psi
histocompatibility 2, class II antigen A, beta, promoter 1
major histocompatibility complex class II beta chain
response to metastatic cancers 1
Abeta
H-2Ab
H2-Ab
I-Abeta
IAb
Ia-2
Ia2
Rmcs1