Pub. Date : 2011
PMID : 21586359
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In fact, the ADORA(2B) requires higher adenosine concentrations than any of the other adenosine receptors. | Adenosine | adenosine A2b receptor | Homo sapiens |
| 2 | However, during conditions of hypoxia or ischemia, the hypoxia-elicited rise in extracellular adenosine is sufficient to activate the ADORA(2B). | Adenosine | adenosine A2b receptor | Homo sapiens |
| 3 | As such, the ADORA(2B) has emerged as a therapeutic target for dampening hypoxia-induced inflammation and tissue adaptation to limited oxygen availability. | Oxygen | adenosine A2b receptor | Homo sapiens |