Title : Nitric oxide modulates lipopolysaccharide-induced endothelial platelet endothelial cell adhesion molecule expression via interleukin-10.

Pub. Date : 2011 Aug

PMID : 21564091






2 Functional Relationships(s)
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1 We have shown previously that nitric oxide (NO) controls platelet endothelial cell adhesion molecule (PECAM-1) expression on both neutrophils and endothelial cells under physiological conditions. Nitric Oxide platelet and endothelial cell adhesion molecule 1 Rattus norvegicus
2 Supernatant of LPS-stimulated lymphocytes obtained from L-NAME-treated rats, which contained higher levels of IL-10, reduced LPS-induced PECAM-1 expression by endothelial cells, and this reduction was reversed by adding the anti-IL-10 monoclonal antibody. NG-Nitroarginine Methyl Ester platelet and endothelial cell adhesion molecule 1 Rattus norvegicus